Agency for Healthcare Research and Quality

This summary explains treatment-resistant depression. It tells you what the most recent research says about the treatment available when medicines do not  help. It gives questions to ask about these treatment options.

American Academy of Family Physicians

The American Academy of Family Physicians discusses about therapy and counseling for treating depression.

Food and Drug Administration

Use this guide to help you talk to your doctor, pharmacist, or nurse about your medicines for depression. The guide lists all of the FDA-approved products now available to treat this condition.


Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They work to balance some of the natural chemicals in our brains. It may take several weeks for them to help. There are several types of antidepressants.

National Institute of Mental Health

The National Institute of Mental Health discusses psychotherapies. Psychotherapy, or "talk therapy", is  a way to treat people with a mental disorder by helping them understand their illness.

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